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Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models
BACKGROUND: Immunocompetent animal models are required to study tumor-host interactions, immunotherapy, and immunotherapeutic combinations, however the currently available immunocompetent lung cancer models have substantial limitations. While orthotopic models potentially help fill this gap, the uti...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455907/ https://www.ncbi.nlm.nih.gov/pubmed/32874131 http://dx.doi.org/10.1186/s12935-020-01503-5 |