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Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models

BACKGROUND: Immunocompetent animal models are required to study tumor-host interactions, immunotherapy, and immunotherapeutic combinations, however the currently available immunocompetent lung cancer models have substantial limitations. While orthotopic models potentially help fill this gap, the uti...

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Detalles Bibliográficos
Autores principales:	Nolan, Kyle, Verzosa, Gregory, Cleaver, Tim, Tippimanchai, Darinee, DePledge, Lisa N., Wang, Xiao-Jing, Young, Christian, Le, Anh, Doebele, Robert, Li, Howard, Malkoski, Stephen P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455907/ https://www.ncbi.nlm.nih.gov/pubmed/32874131 http://dx.doi.org/10.1186/s12935-020-01503-5

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