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Assessment of tumor suppressor promoter methylation in healthy individuals

BACKGROUND: The number of tumor suppressor genes for which germline mutations have been linked to cancer risk is steadily increasing. However, while recent reports have linked constitutional normal tissue promoter methylation of BRCA1 and MLH1 to ovarian and colon cancer risk, the role of epigenetic...

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Detalles Bibliográficos
Autores principales:	Poduval, Deepak B., Ognedal, Elisabet, Sichmanova, Zuzana, Valen, Eivind, Iversen, Gjertrud T., Minsaas, Laura, Lønning, Per E., Knappskog, Stian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455917/ https://www.ncbi.nlm.nih.gov/pubmed/32859265 http://dx.doi.org/10.1186/s13148-020-00920-7

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