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Hexokinase inhibition using D-Mannoheptulose enhances oncolytic newcastle disease virus-mediated killing of breast cancer cells

BACKGROUND: Most cancer cells exhibit increased glycolysis and use this metabolic pathway cell growth and proliferation. Targeting cancer cells’ metabolism is a promising strategy in inhibiting cancer cell progression. We used D-Mannoheptulose, a specific hexokinase inhibitor, to inhibit glycolysis...

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Detalles Bibliográficos
Autores principales:	Al-Ziaydi, Ahmed Ghdhban, Al-Shammari, Ahmed Majeed, Hamzah, Mohammed I., kadhim, Haider Sabah, Jabir, Majid Sakhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456035/ https://www.ncbi.nlm.nih.gov/pubmed/32874134 http://dx.doi.org/10.1186/s12935-020-01514-2

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