Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300

Fibrotic diseases remain a major cause of morbidity and mortality, yet there are few effective therapies. The underlying pathology of all fibrotic conditions is the activity of myofibroblasts. Using cells from freshly excised disease tissue from patients with Dupuytren’s disease (DD), a localized fi...

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Detalles Bibliográficos
Autores principales: Williams, Lynn M., McCann, Fiona E., Cabrita, Marisa A., Layton, Thomas, Cribbs, Adam, Knezevic, Bogdan, Fang, Hai, Knight, Julian, Zhang, Mingjun, Fischer, Roman, Bonham, Sarah, Steenbeek, Leenart M., Yang, Nan, Sood, Manu, Bainbridge, Chris, Warwick, David, Harry, Lorraine, Davidson, Dominique, Xie, Weilin, Sundstrӧm, Michael, Feldmann, Marc, Nanchahal, Jagdeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456151/
https://www.ncbi.nlm.nih.gov/pubmed/32759223
http://dx.doi.org/10.1073/pnas.2004281117

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