Involvement of p53, p21, and Caspase-3 in Apoptosis of Coronary Artery Smooth Muscle Cells in a Kawasaki Vasculitis Mouse Model

BACKGROUND: Overexpression of p53, p21, and caspase-3 promotes apoptosis of vascular smooth muscle cells. However, the mechanisms that lead to apoptosis of coronary artery smooth muscle cells (CASMCs) is unclear in Kawasaki disease (KD). This study investigated involvement of p53, p21, and caspase-3...

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Detalles Bibliográficos
Autores principales: Deng, Minghong, Lin, Chunwang, Zeng, Xianglin, Zhang, Jianping, Wen, Fang, Liu, Ziguang, Wu, Haiyan, Wu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456161/
https://www.ncbi.nlm.nih.gov/pubmed/32820144
http://dx.doi.org/10.12659/MSM.922429

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