Diabetes and COVID-19: A pooled analysis related to disease severity and mortality

Globally, COVID-19 has become a major concern for the diabetic community. We conducted a pooled analysis and constructed a forest plot for the association between diabetes and COVID-19 progression in 47 studies. A random effects meta-analysis (Mantel–Haenszel method) was conducted to estimate the ou...

Descripción completa

Detalles Bibliográficos
Autores principales: Varikasuvu, Seshadri Reddy, Dutt, Naveen, Thangappazham, Balachandar, Varshney, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Primary Care Diabetes Europe. Published by Elsevier Ltd. 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456278/
https://www.ncbi.nlm.nih.gov/pubmed/32891525
http://dx.doi.org/10.1016/j.pcd.2020.08.015
_version_ 1783575768311267328
author Varikasuvu, Seshadri Reddy
Dutt, Naveen
Thangappazham, Balachandar
Varshney, Saurabh
author_facet Varikasuvu, Seshadri Reddy
Dutt, Naveen
Thangappazham, Balachandar
Varshney, Saurabh
author_sort Varikasuvu, Seshadri Reddy
collection PubMed
description Globally, COVID-19 has become a major concern for the diabetic community. We conducted a pooled analysis and constructed a forest plot for the association between diabetes and COVID-19 progression in 47 studies. A random effects meta-analysis (Mantel–Haenszel method) was conducted to estimate the outcomes effect size as odds ratios (OR) and 95% confidence intervals (CI) using Review Manager Software version 5.3. COVID-19 patients with diabetes have a significantly higher risk of disease severity (OR = 2.20, 95% CI = 1.69–2.86, p < 0.00001) and associated mortality outcomes (OR = 2.52, 95% CI = 1.93–3.30, p =  < 0.00001).
format Online
Article
Text
id pubmed-7456278
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Primary Care Diabetes Europe. Published by Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-74562782020-08-31 Diabetes and COVID-19: A pooled analysis related to disease severity and mortality Varikasuvu, Seshadri Reddy Dutt, Naveen Thangappazham, Balachandar Varshney, Saurabh Prim Care Diabetes Brief Report Globally, COVID-19 has become a major concern for the diabetic community. We conducted a pooled analysis and constructed a forest plot for the association between diabetes and COVID-19 progression in 47 studies. A random effects meta-analysis (Mantel–Haenszel method) was conducted to estimate the outcomes effect size as odds ratios (OR) and 95% confidence intervals (CI) using Review Manager Software version 5.3. COVID-19 patients with diabetes have a significantly higher risk of disease severity (OR = 2.20, 95% CI = 1.69–2.86, p < 0.00001) and associated mortality outcomes (OR = 2.52, 95% CI = 1.93–3.30, p =  < 0.00001). Primary Care Diabetes Europe. Published by Elsevier Ltd. 2021-02 2020-08-29 /pmc/articles/PMC7456278/ /pubmed/32891525 http://dx.doi.org/10.1016/j.pcd.2020.08.015 Text en © 2020 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Report
Varikasuvu, Seshadri Reddy
Dutt, Naveen
Thangappazham, Balachandar
Varshney, Saurabh
Diabetes and COVID-19: A pooled analysis related to disease severity and mortality
title Diabetes and COVID-19: A pooled analysis related to disease severity and mortality
title_full Diabetes and COVID-19: A pooled analysis related to disease severity and mortality
title_fullStr Diabetes and COVID-19: A pooled analysis related to disease severity and mortality
title_full_unstemmed Diabetes and COVID-19: A pooled analysis related to disease severity and mortality
title_short Diabetes and COVID-19: A pooled analysis related to disease severity and mortality
title_sort diabetes and covid-19: a pooled analysis related to disease severity and mortality
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456278/
https://www.ncbi.nlm.nih.gov/pubmed/32891525
http://dx.doi.org/10.1016/j.pcd.2020.08.015
work_keys_str_mv AT varikasuvuseshadrireddy diabetesandcovid19apooledanalysisrelatedtodiseaseseverityandmortality
AT duttnaveen diabetesandcovid19apooledanalysisrelatedtodiseaseseverityandmortality
AT thangappazhambalachandar diabetesandcovid19apooledanalysisrelatedtodiseaseseverityandmortality
AT varshneysaurabh diabetesandcovid19apooledanalysisrelatedtodiseaseseverityandmortality

Ejemplares similares