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Short-term and longer-term protective immune responses generated by subunit vaccination with smallpox A33, B5, L1 or A27 proteins adjuvanted with aluminum hydroxide and CpG in mice challenged with vaccinia virus
Smallpox, a contagious and deadly disease caused by variola virus, was eradicated by a strategy that included vaccination with vaccinia virus, a live-virus vaccine. Because the threat of bioterrorism with smallpox persists and infections with zoonotic poxvirus infections like monkeypox continue, and...
Autores principales: | Xiao, Yuhong, Zeng, Yuhong, Schante, Carole, Joshi, Sangeeta B., Buchman, George W., Volkin, David B., Middaugh, C. Russell, Isaacs, Stuart N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456309/ https://www.ncbi.nlm.nih.gov/pubmed/32741672 http://dx.doi.org/10.1016/j.vaccine.2020.07.018 |
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