Cargando…

Diversity in the intrinsic apoptosis pathway of nematodes

Early studies of the free-living nematode C. elegans informed us how BCL-2-regulated apoptosis in humans is regulated. However, subsequent studies showed C. elegans apoptosis has several unique features compared with human apoptosis. To date, there has been no detailed analysis of apoptosis regulato...

Descripción completa

Detalles Bibliográficos
Autores principales:	Young, Neil D., Harris, Tiffany J., Evangelista, Marco, Tran, Sharon, Wouters, Merridee A., Soares da Costa, Tatiana P., Kershaw, Nadia J., Gasser, Robin B., Smith, Brian J., Lee, Erinna F., Fairlie, W. Douglas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456325/ https://www.ncbi.nlm.nih.gov/pubmed/32859965 http://dx.doi.org/10.1038/s42003-020-01208-5

Ejemplares similares

Structural biology of the intrinsic cell death pathway: what do we know and what is missing?
por: Lee, Erinna F., et al.
Publicado: (2012)

BECLIN1: Protein Structure, Function and Regulation
por: Tran, Sharon, et al.
Publicado: (2021)

The emerging roles of autophagy in intestinal epithelial cells and its links to inflammatory bowel disease
por: Tran, Sharon, et al.
Publicado: (2023)

The Structural Biology of Bcl-x(L)
por: Lee, Erinna F., et al.
Publicado: (2019)

Co-Operativity between MYC and BCL-2 Pro-Survival Proteins in Cancer
por: Fairlie, Walter Douglas, et al.
Publicado: (2021)

Discovery, development and application of drugs targeting BCL-2 pro-survival proteins in cancer
por: Lee, Erinna F., et al.
Publicado: (2021)

Targeting the BCL-2-regulated apoptotic pathway for the treatment of solid cancers
por: Fairlie, W. Douglas, et al.
Publicado: (2021)

Induction of endoplasmic reticulum stress is associated with the anti‐tumor activity of monepantel across cancer types
por: Harris, Tiffany J., et al.
Publicado: (2023)

BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival
por: Lee, Erinna F., et al.
Publicado: (2019)

Prospects of Using High-Throughput Proteomics to Underpin the Discovery of Animal Host–Nematode Interactions
por: Wang, Tao, et al.
Publicado: (2021)

An appraisal of natural products active against parasitic nematodes of animals
por: Garcia-Bustos, Jose F., et al.
Publicado: (2019)

Correction: BCL-XL is an actionable target for treatment of malignant pleural mesothelioma
por: Arulananda, Surein, et al.
Publicado: (2021)

Advances in the diagnosis of key gastrointestinal nematode infections of livestock, with an emphasis on small ruminants
por: Roeber, Florian, et al.
Publicado: (2013)

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation
por: Lee, Erinna F., et al.
Publicado: (2008)

Repurposing of a human antibody-based microarray to explore conserved components of the signalome of the parasitic nematode Haemonchus contortus
por: Adderley, Jack, et al.
Publicado: (2022)

Mathematical modeling of the formation of apoptosome in intrinsic pathway of apoptosis
por: Ryu, Seongho, et al.
Publicado: (2009)

Antibody isotype analysis of malaria-nematode co-infection: problems and solutions associated with cross-reactivity
por: Fairlie-Clarke, Karen J, et al.
Publicado: (2010)

BCL-XL is an actionable target for treatment of malignant pleural mesothelioma
por: Arulananda, Surein, et al.
Publicado: (2020)

Next-Generation Molecular-Diagnostic Tools for Gastrointestinal Nematodes of Livestock, with an Emphasis on Small Ruminants: A Turning Point?
por: Roeber, Florian, et al.
Publicado: (2013)

Phylogenetic Relationships of the Strongyloid Nematodes of Australasian Marsupials Based on Mitochondrial Protein Sequences
por: Sukee, Tanapan, et al.
Publicado: (2022)

Impact of gastrointestinal parasitic nematodes of sheep, and the role of advanced molecular tools for exploring epidemiology and drug resistance - an Australian perspective
por: Roeber, Florian, et al.
Publicado: (2013)

Tv-RIO1 – an atypical protein kinase from the parasitic nematode Trichostrongylus vitrinus
por: Hu, Min, et al.
Publicado: (2008)

Systematic analysis of insertions and deletions specific to nematode proteins and their proposed functional and evolutionary relevance
por: Wang, Zhengyuan, et al.
Publicado: (2009)

Comparison of automated candidate gene prediction systems using genes implicated in type 2 diabetes by genome-wide association studies
por: Teber, Erdahl T, et al.
Publicado: (2009)

Overcoming Intrinsic and Acquired Resistance Mechanisms Associated with the Cell Wall of Gram-Negative Bacteria
por: Impey, Rachael E., et al.
Publicado: (2020)

Mitochondrial Phylogenomics yields Strongly Supported Hypotheses for Ascaridomorph Nematodes
por: Liu, Guo-Hua, et al.
Publicado: (2016)

Needles in the EST Haystack: Large-Scale Identification and Analysis of Excretory-Secretory (ES) Proteins in Parasitic Nematodes Using Expressed Sequence Tags (ESTs)
por: Nagaraj, Shivashankar H., et al.
Publicado: (2008)

The Mitochondrial Protein NLRX1 Controls the Balance between Extrinsic and Intrinsic Apoptosis
por: Soares, Fraser, et al.
Publicado: (2014)

Nematodes Go Viral
por: Meadows, Robin
Publicado: (2011)

Identifying foldable regions in protein sequence from the hydrophobic signal
por: Pang, Chi N.I., et al.
Publicado: (2008)

Nesfatin-1 puts the brakes on reward-based feeding
por: Lefner, Merridee J., et al.
Publicado: (2020)

Intrinsically Disordered Proteins in Bcl-2 Regulated Apoptosis
por: Rautureau, Gilles J. P., et al.
Publicado: (2010)

Dispersal and Repulsion of Entomopathogenic Nematodes to Prenol
por: Kin, Kassandra, et al.
Publicado: (2019)

Analysis of protein sequence and interaction data for candidate disease gene prediction
por: George, Richard A., et al.
Publicado: (2006)

The behaviour of nematodes: their activity, senses and responses
por: Croll, Neil Argo
Publicado: (1970)

Immunity to gastrointestinal nematodes: mechanisms and myths
por: Grencis, Richard K, et al.
Publicado: (2014)

Regulation of apoptosis by an intrinsically disordered region of Bcl-xL
por: Follis, Ariele Viacava, et al.
Publicado: (2018)

The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus
por: Schwarz, Erich M, et al.
Publicado: (2013)

Phylogenetic relationships of the nematode subfamily Phascolostrongylinae from macropodid and vombatid marsupials inferred using mitochondrial protein sequence data
por: Sukee, Tanapan, et al.
Publicado: (2021)

A suicide inhibitor of nematode trehalose-6-phosphate phosphatases
por: Cross, Megan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_onhi8552g6v1730vfld9lgvj2j