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Compound amino acid combined with high-dose vitamin B6 attenuate traumatic coagulopathy via inhibiting inflammation by HMGB1/TLR4/NF-κB pathway

BACKGROUND: Traumatic coagulopathy (TC) arises primarily from coagulation system failure to maintain adequate hemostasis after serious blood loss or trauma. Circulatory homeostasis restoration is the mainstay of the therapeutic approach to TC, but the effects are significantly inhibited by coagulopa...

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Detalles Bibliográficos
Autores principales:	Yi, Shi-Jian, Wu, Yang, Li, Lan-Lan, Liang, Qian-Kun, Xiao, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456387/ https://www.ncbi.nlm.nih.gov/pubmed/32874136 http://dx.doi.org/10.1186/s12950-020-00258-0

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