Nlrp3 Inflammasome Signaling Regulates the Homing and Engraftment of Hematopoietic Stem Cells (HSPCs) by Enhancing Incorporation of CXCR4 Receptor into Membrane Lipid Rafts

Fast and efficient homing and engraftment of hematopoietic stem progenitor cells (HSPCs) is crucial for positive clinical outcomes from transplantation. We found that this process depends on activation of the Nlrp3 inflammasome, both in the HSPCs to be transplanted and in the cells in the recipient...

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Detalles Bibliográficos
Autores principales: Adamiak, Mateusz, Abdel-Latif, Ahmed, Bujko, Kamila, Thapa, Arjun, Anusz, Krzysztof, Tracz, Michał, Brzezniakiewicz-Janus, Katarzyna, Ratajczak, Janina, Kucia, Magda, Ratajczak, Mariusz Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456406/
https://www.ncbi.nlm.nih.gov/pubmed/32661868
http://dx.doi.org/10.1007/s12015-020-10005-w

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