Cargando…

GPA Peptide-Induced Nur77 Localization at Mitochondria Inhibits Inflammation and Oxidative Stress through Activating Autophagy in the Intestine

Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disease affecting the colon, and its incidence is rising worldwide. Nur77, belongs to the NR4A subfamily of nuclear hormone receptors, plays a critical role in controlling the...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Zhao, Liu, Qi, Wang, Miaomiao, Wei, Hong-Kui, Peng, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456482/
https://www.ncbi.nlm.nih.gov/pubmed/32904539
http://dx.doi.org/10.1155/2020/4964202