Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Modifications

The coronavirus disease 2019 (COVID-19) pandemic has led to worldwide efforts to understand the biological traits of the newly identified human coronavirus (HCoV-19) virus. In this mass spectrometry (MS)-based study, we reveal that out of 21 possible glycosites in the HCoV-19 spike protein (S protei...

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Detalles Bibliográficos
Autores principales: Sun, Zeyu, Ren, Keyi, Zhang, Xing, Chen, Jinghua, Jiang, Zhengyi, Jiang, Jing, Ji, Feiyang, Ouyang, Xiaoxi, Li, Lanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: THE AUTHORS. Published by Elsevier LTD on behalf of Chinese Academy of Engineering and Higher Education Press Limited Company. 2021
Materias:
Research Coronavirus Disease 2019—Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456593/
https://www.ncbi.nlm.nih.gov/pubmed/32904601
http://dx.doi.org/10.1016/j.eng.2020.07.014

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