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Prefilled Cyclic Olefin Sterilized Syringes of Norepinephrine Injection Solution Do Not Need to Be Stabilized by Antioxidants

Norepinephrine is a potent α-sympathomimetic drug which plays an important role in the acute treatment of hypotension and shock. Commercially available norepinephrine solutions contain sodium metabisulfite (Na2S2O5) as an antioxidant. However, prefilled cyclic olefin polymer syringes are not compati...

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Detalles Bibliográficos
Autores principales:	Larmené- Beld, Karin H. M., van Berkel, Stefan, Wijnsma, Rommert, Taxis, Katja, Frijlink, Henderik W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456634/ https://www.ncbi.nlm.nih.gov/pubmed/32862255 http://dx.doi.org/10.1208/s12249-020-01784-z

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