Pharmacological inhibition of poly (ADP-ribose) polymerase by olaparib ameliorates influenza-virus-induced pneumonia in mice

Treatments against influenza A viruses (IAV) have to be updated regularly due to antigenic drift and drug resistance. Poly (ADP-ribose) polymerases (PARPs) are considered effective therapeutic targets of acute lung inflammatory injury. This study aimed to explore the effects of PARP-1 inhibitor olap...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Ren, Xiaojuan, Wang, Qian, Zhang, Yan, Du, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456638/
https://www.ncbi.nlm.nih.gov/pubmed/32865668
http://dx.doi.org/10.1007/s10096-020-04020-5

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