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Prevalence and outcomes of re-positive nucleic acid tests in discharged COVID-19 patients

The prevalence and outcomes of patients who had re-activation of coronavirus disease 2019 (COVID-19) after discharge remain poorly understood. We included 126 consecutively confirmed cases of COVID-19 with 2-month follow-up data after discharge in this retrospective study. The upper respiratory spec...

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Detalles Bibliográficos
Autores principales: Du, Hou-wei, Chen, Jun-nian, Pan, Xiao-bin, Chen, Xiao-ling, Yixian-Zhang, Fang, Shuang-fang, Li, Xiao-qing, Xia, Pin-cang, Gao, Lei, Lin, Hai-long, Chen, Li-min, Liu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456660/
https://www.ncbi.nlm.nih.gov/pubmed/32865669
http://dx.doi.org/10.1007/s10096-020-04024-1
Descripción
Sumario:The prevalence and outcomes of patients who had re-activation of coronavirus disease 2019 (COVID-19) after discharge remain poorly understood. We included 126 consecutively confirmed cases of COVID-19 with 2-month follow-up data after discharge in this retrospective study. The upper respiratory specimen using a reverse-transcription polymerase chain reaction test of three patients (71 years [60–76]) were positive within 11–20 days after their discharge, with an event rate of 19.8 (95%CI 2.60–42.1) per 1,000,000 patient-days. Moreover, all re-positive patients were asymptomatic. Our findings suggest that few recovered patients may still be virus carriers even after reaching the discharge criteria. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10096-020-04024-1) contains supplementary material, which is available to authorized users.