Statistical design of Phase II/III clinical trials for testing therapeutic interventions in COVID-19 patients

BACKGROUND: Because of unknown features of the COVID-19 and the complexity of the population affected, standard clinical trial designs on treatments may not be optimal in such patients. We propose two independent clinical trials designs based on careful grouping of patient and outcome measures. METH...

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Detalles Bibliográficos
Autores principales: Rai, Shesh N., Qian, Chen, Pan, Jianmin, Seth, Anand, Srivastava, Deo Kumar, Bhatnagar, Aruni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456751/
https://www.ncbi.nlm.nih.gov/pubmed/32867708
http://dx.doi.org/10.1186/s12874-020-01101-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456751/
https://www.ncbi.nlm.nih.gov/pubmed/32867708
http://dx.doi.org/10.1186/s12874-020-01101-z

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