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Rapid detection of biomolecules in a dielectric modulated GaN MOSHEMT

Biosensors are the devices that find application in almost every field nowadays. In this paper, GaN MOSHEMT based biosensor is proposed for detection of biomolecules such as ChOx, protein, streptavidin and Uricase. The effect of biomolecule species on the performance parameters of the device has bee...

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Detalles Bibliográficos
Autores principales: Shaveta, Ahmed, H. M. Maali, Chaujar, Rishu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456762/
http://dx.doi.org/10.1007/s10854-020-04216-7
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author Shaveta
Ahmed, H. M. Maali
Chaujar, Rishu
author_facet Shaveta
Ahmed, H. M. Maali
Chaujar, Rishu
author_sort Shaveta
collection PubMed
description Biosensors are the devices that find application in almost every field nowadays. In this paper, GaN MOSHEMT based biosensor is proposed for detection of biomolecules such as ChOx, protein, streptavidin and Uricase. The effect of biomolecule species on the performance parameters of the device has been studied. It has been observed that there is a significant increase in the drain current and g(d) is observed with the addition of biomolecule in the nanocavity. The electron concentration contour is studied which shows the rise of carrier concentration with biomolecule. Maximum positive shift is observed in threshold voltage for Uricase due to lowest dielectric constant. Similarly, the change in transconductance is also obtained with biomolecules. The effect of cavity dimensions on sensitivity is also studied. The maximum increase of 10% in channel potential is noted due biomolecule presence in the cavity. This device has shown good sensing and can be used for biosensing applications efficiently in addition to the high power performance of MOS-HEMTs.
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spelling pubmed-74567622020-08-31 Rapid detection of biomolecules in a dielectric modulated GaN MOSHEMT Shaveta Ahmed, H. M. Maali Chaujar, Rishu J Mater Sci: Mater Electron Article Biosensors are the devices that find application in almost every field nowadays. In this paper, GaN MOSHEMT based biosensor is proposed for detection of biomolecules such as ChOx, protein, streptavidin and Uricase. The effect of biomolecule species on the performance parameters of the device has been studied. It has been observed that there is a significant increase in the drain current and g(d) is observed with the addition of biomolecule in the nanocavity. The electron concentration contour is studied which shows the rise of carrier concentration with biomolecule. Maximum positive shift is observed in threshold voltage for Uricase due to lowest dielectric constant. Similarly, the change in transconductance is also obtained with biomolecules. The effect of cavity dimensions on sensitivity is also studied. The maximum increase of 10% in channel potential is noted due biomolecule presence in the cavity. This device has shown good sensing and can be used for biosensing applications efficiently in addition to the high power performance of MOS-HEMTs. Springer US 2020-08-31 2020 /pmc/articles/PMC7456762/ http://dx.doi.org/10.1007/s10854-020-04216-7 Text en © Springer Science+Business Media, LLC, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Shaveta
Ahmed, H. M. Maali
Chaujar, Rishu
Rapid detection of biomolecules in a dielectric modulated GaN MOSHEMT
title Rapid detection of biomolecules in a dielectric modulated GaN MOSHEMT
title_full Rapid detection of biomolecules in a dielectric modulated GaN MOSHEMT
title_fullStr Rapid detection of biomolecules in a dielectric modulated GaN MOSHEMT
title_full_unstemmed Rapid detection of biomolecules in a dielectric modulated GaN MOSHEMT
title_short Rapid detection of biomolecules in a dielectric modulated GaN MOSHEMT
title_sort rapid detection of biomolecules in a dielectric modulated gan moshemt
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456762/
http://dx.doi.org/10.1007/s10854-020-04216-7
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