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Effect of withholding early parenteral nutrition in PICU on ketogenesis as potential mediator of its outcome benefit
BACKGROUND: In critically ill children, omitting early use of parenteral nutrition (late-PN versus early-PN) reduced infections, accelerated weaning from mechanical ventilation, and shortened PICU stay. We hypothesized that fasting-induced ketogenesis mediates these benefits. METHODS: In a secondary...
Autores principales: | De Bruyn, Astrid, Gunst, Jan, Goossens, Chloë, Vander Perre, Sarah, Guerra, Gonzalo G., Verbruggen, Sascha, Joosten, Koen, Langouche, Lies, Van den Berghe, Greet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456767/ https://www.ncbi.nlm.nih.gov/pubmed/32867803 http://dx.doi.org/10.1186/s13054-020-03256-z |
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