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Wheel-Running Behavior Is Negatively Impacted by Zinc Administration in a Novel Dual Transgenic Mouse Model of AD
Alzheimer’s disease (AD) is a neurocognitive disorder that impacts both the brain and behavior. Metal ions, including zinc (Zn), have been seen to play an important role in AD-related pathology. In this study, we show alterations in wheel-running behavior both early and late in disease progression i...
Autores principales: | Lippi, Stephen L. P., Kakalec, Peter A., Smith, Meghann L., Flinn, Jane M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456872/ https://www.ncbi.nlm.nih.gov/pubmed/32922260 http://dx.doi.org/10.3389/fnins.2020.00854 |
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