Cargando…

Hypoxia-Induced Adipose Lipolysis Requires Fibroblast Growth Factor 21

Fibroblast growth factor 21 (FGF21) is a recently discovered hepatokine that regulates lipid and glucose metabolism and is upregulated in response to numerous physiological and pathological stimuli. Herein, we demonstrate that both physical and chemical hypoxia increase the systemic and hepatic expr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Guicheng, Liu, Yanlong, Feng, Wenke, An, Xuan, Lin, Wenhui, Tang, Chengwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456904/ https://www.ncbi.nlm.nih.gov/pubmed/32922298 http://dx.doi.org/10.3389/fphar.2020.01279

Ejemplares similares

Fibroblast Growth Factor 21 Deficiency Attenuates Experimental Colitis-Induced Adipose Tissue Lipolysis
por: Liu, Liming, et al.
Publicado: (2017)

FGF21 mediates alcohol-induced adipose tissue lipolysis by activation of systemic release of catecholamine in mice
por: Zhao, Cuiqing, et al.
Publicado: (2015)

Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance
por: Xiao, Na, et al.
Publicado: (2017)

Fibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injury
por: Liu, Yanlong, et al.
Publicado: (2016)

Emerging roles of fibroblast growth factor 21 in critical disease
por: Yan, Fang, et al.
Publicado: (2022)

Bibliometric analysis of fibroblast growth factor 21 research over the period 2000 to 2021
por: She, Qin-Ying, et al.
Publicado: (2022)

Pyrrolidine Dithiocarbamate (PDTC) Attenuates Cancer Cachexia by Affecting Muscle Atrophy and Fat Lipolysis
por: Miao, Chunxiao, et al.
Publicado: (2017)

Basic Fibroblast Growth Factor Attenuates Injury in Myocardial Infarction by Enhancing Hypoxia-Inducible Factor-1 Alpha Accumulation
por: Rao, Zhiheng, et al.
Publicado: (2020)

Fibroblast Growth Factors in Depression
por: Deng, Zheng, et al.
Publicado: (2019)

Toxicokinetics of recombinant human fibroblast growth factor 21 for injection in cynomolgus monkey for 3 months
por: Lu, Chao, et al.
Publicado: (2023)

Effects of acute hypoxia on human adipose tissue lipoprotein lipase activity and lipolysis
por: Mahat, Bimit, et al.
Publicado: (2016)

Fibroblast Growth Factor 21 Ameliorates Na(V)1.5 and Kir2.1 Channel Dysregulation in Human AC16 Cardiomyocytes
por: Li, Jiamin, et al.
Publicado: (2021)

Fibroblast Growth Factor 21 and Browning of White Adipose Tissue
por: Cuevas-Ramos, Daniel, et al.
Publicado: (2019)

Correction to: Effects of acute hypoxia on human adipose tissue lipoprotein lipase activity and lipolysis
por: Mahat, Bimit, et al.
Publicado: (2021)

Systemic Administration of Fibroblast Growth Factor 21 Improves the Recovery of Spinal Cord Injury (SCI) in Rats and Attenuates SCI-Induced Autophagy
por: Zhu, Sipin, et al.
Publicado: (2021)

CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis
por: Park, Jong-Gil, et al.
Publicado: (2016)

Fibroblast Growth Factor 1 Ameliorates Diabetes-Induced Liver Injury by Reducing Cellular Stress and Restoring Autophagy
por: Xu, Zeping, et al.
Publicado: (2020)

The Molecular Brakes of Adipose Tissue Lipolysis
por: Li, Yongguo, et al.
Publicado: (2022)

Feedback Activation of Basic Fibroblast Growth Factor Signaling via the Wnt/β-Catenin Pathway in Skin Fibroblasts
por: Wang, Xu, et al.
Publicado: (2017)

Growth hormone stimulates lipolysis in mice but not in adipose tissue or adipocyte culture
por: Zhao, Lidan, et al.
Publicado: (2023)

Metabolic role of fibroblast growth factor 21 in liver, adipose and nervous system tissues
por: Lin, Xiaolong, et al.
Publicado: (2017)

Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats
por: Sarruf, David A., et al.
Publicado: (2010)

Fibroblast growth factor 21 is required for the therapeutic effects of Lactobacillus rhamnosus GG against fructose-induced fatty liver in mice
por: Zhao, Cuiqing, et al.
Publicado: (2019)

Fibroblast growth factor 21 associating with serotonin and dopamine in the cerebrospinal fluid predicts impulsivity in healthy subjects
por: Xu, Jinzhong, et al.
Publicado: (2021)

Roles of Fibroblast Growth Factors and Their Therapeutic Potential in Treatment of Ischemic Stroke
por: Dordoe, Confidence, et al.
Publicado: (2021)

Fibroblast Growth Factor 21 (FGF21) in Human Cerebrospinal Fluid: Relationship With Plasma FGF21 and Body Adiposity
por: Tan, Bee K., et al.
Publicado: (2011)

GPCR in Adipose Tissue Function—Focus on Lipolysis
por: Malfacini, Davide, et al.
Publicado: (2023)

Hypoxia and Hypoxia-Inducible Factors in Lymphedema
por: Jiang, Xinguo, et al.
Publicado: (2022)

The Role of Fibroblast Growth Factor 10 Signaling in Duodenal Atresia
por: Jones, Matthew L. M., et al.
Publicado: (2020)

Fibroblast growth factor 21 and bone homeostasis
por: Tang, Yan, et al.
Publicado: (2023)

Metabonomic analysis of abnormal sphingolipid metabolism in rheumatoid arthritis synovial fibroblasts in hypoxia microenvironment and intervention of geniposide
por: Ke, Jiang-Tao, et al.
Publicado: (2022)

Endoplasmic reticulum stress in adipose tissue augments lipolysis
por: Bogdanovic, Elena, et al.
Publicado: (2015)

Periparturient lipolysis and oxylipid biosynthesis in bovine adipose tissues
por: Contreras, G. Andres, et al.
Publicado: (2017)

Protocol for assessing exvivo lipolysis of murine adipose tissue
por: Roy, Debasish, et al.
Publicado: (2022)

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
por: Xu, Jing, et al.
Publicado: (2009)

Fibroblast Growth Factors in the Management of Acute Kidney Injury Following Ischemia-Reperfusion
por: Deng, Lian-Cheng, et al.
Publicado: (2020)

FGF21 Protects Against Hypoxia Injury Through Inducing HSP72 in Cerebral Microvascular Endothelial Cells
por: Wang, Hao-Wei, et al.
Publicado: (2019)

Dietary Intake Regulates White Adipose Tissues Angiogenesis via Liver Fibroblast Growth Factor 21 in Male Mice
por: Hua, Lun, et al.
Publicado: (2020)

Editorial: The Fibroblast Growth Factor Signaling Pathway in Metabolic Regulation, Development, Disease, and Repair After Injury
por: Wang, Zhouguang, et al.
Publicado: (2020)

SIRT Is Required for EDP-Mediated Protective Responses toward Hypoxia–Reoxygenation Injury in Cardiac Cells
por: Samokhvalov, Victor, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_9djj28ovrvf7ebifqpduq2sq6a