Partial Degradation of Recombinant Antibody Functional Activity During Infant Gastrointestinal Digestion: Implications for Oral Antibody Supplementation

Oral administration of engineered immunoglobulins has the potential to prevent enteric pathogen-induced diarrhea in infants. To prevent infection, these antibodies need to survive functionally intact in the proteolytic environment of the gastrointestinal tract. This research examined both ex vivo an...

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Detalles Bibliográficos
Autores principales: Sah, Baidya Nath P., Lueangsakulthai, Jiraporn, Kim, Bum Jin, Hauser, Benjamin R., Woo, Yeonhee, Olyaei, Amy, Aloia, Molly, O'Connor, Ann, Scottoline, Brian, Pastey, Manoj K., Dallas, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456970/
https://www.ncbi.nlm.nih.gov/pubmed/32923453
http://dx.doi.org/10.3389/fnut.2020.00130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456970/
https://www.ncbi.nlm.nih.gov/pubmed/32923453
http://dx.doi.org/10.3389/fnut.2020.00130

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