CR4 Signaling Contributes to a DC-Driven Enhanced Immune Response Against Complement-Opsonized HIV-1

Dendritic cells (DCs) possess intrinsic cellular defense mechanisms to specifically inhibit HIV-1 replication. In turn, HIV-1 has evolved strategies to evade innate immune sensing by DCs resulting in suboptimal maturation and poor antiviral immune responses. We previously showed that complement-opso...

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Detalles Bibliográficos
Autores principales: Bermejo-Jambrina, Marta, Blatzer, Michael, Jauregui-Onieva, Paula, Yordanov, Teodor E., Hörtnagl, Paul, Valovka, Taras, Huber, Lukas A., Wilflingseder, Doris, Posch, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457048/
https://www.ncbi.nlm.nih.gov/pubmed/32922405
http://dx.doi.org/10.3389/fimmu.2020.02010

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