Poly C Binding Protein 1 Regulates p62/SQSTM1 mRNA Stability and Autophagic Degradation to Repress Tumor Progression

Accumulating evidence show that Poly C Binding Protein 1 (PCBP1) is deleted in distinct types of tumors as a novel tumor suppressor, but its tumor suppression mechanism remains elusive. Here, we firstly describe that downregulation of PCBP1 is significantly associated with clinical ovarian tumor pro...

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Detalles Bibliográficos
Autores principales: Zhang, Wenliang, Zhang, Shaoyang, Guan, Wen, Huang, Zhicong, Kong, Jianqiu, Huang, Chunlong, Wang, Haihe, Yang, Shulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457068/
https://www.ncbi.nlm.nih.gov/pubmed/32922440
http://dx.doi.org/10.3389/fgene.2020.00930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457068/
https://www.ncbi.nlm.nih.gov/pubmed/32922440
http://dx.doi.org/10.3389/fgene.2020.00930

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