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T-Cell Immunodeficiencies With Congenital Alterations of Thymic Development: Genes Implicated and Differential Immunological and Clinical Features
Combined Immunodeficiencies (CID) are rare congenital disorders characterized by defective T-cell development that may be associated with B- and NK-cell deficiency. They are usually due to alterations in genes expressed in hematopoietic precursors but in few cases, they are caused by impaired thymic...
Autores principales: | Giardino, Giuliana, Borzacchiello, Carla, De Luca, Martina, Romano, Roberta, Prencipe, Rosaria, Cirillo, Emilia, Pignata, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457079/ https://www.ncbi.nlm.nih.gov/pubmed/32922396 http://dx.doi.org/10.3389/fimmu.2020.01837 |
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