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The mTOR/ULK1 signaling pathway mediates the autophagy-promoting and osteogenic effects of dicalcium silicate nanoparticles

A novel bioactive inorganic material containing silicon, calcium and oxygen, calcium silicate (Ca(2)SiO(4), C(2)S) with a CaO-SiO(2) ingredient, has been identified as a potential candidate for artificial bone. Autophagy has an essential function in adult tissue homoeostasis and tumorigenesis. Howev...

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Detalles Bibliográficos
Autores principales:	Ruolan, Wang, Liangjiao, Chen, Longquan, Shao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457372/ https://www.ncbi.nlm.nih.gov/pubmed/32867795 http://dx.doi.org/10.1186/s12951-020-00663-w

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