Cargando…
The Ambiguous Role of Microglia in Aβ Toxicity: Chances for Therapeutic Intervention
Amyloid-β (Aβ) has long been shown to be critical in Alzheimer’s disease pathophysiology. Microglia contributes to the earliest responses to Aβ buildup, by direct interaction through multiple receptors. Microglial cells operate Aβ clearance and trigger inflammatory/regenerative processes that take p...
Autores principales: | Merlo, Sara, Spampinato, Simona Federica, Caruso, Grazia Ilaria, Sortino, Maria Angela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457435/ https://www.ncbi.nlm.nih.gov/pubmed/32003695 http://dx.doi.org/10.2174/1570159X18666200131105418 |
Ejemplares similares
-
SIRT1-Dependent Upregulation of BDNF in Human Microglia Challenged with Aβ: An Early but Transient Response Rescued by Melatonin
por: Caruso, Grazia Ilaria, et al.
Publicado: (2021) -
The contribution of microglia to early synaptic compensatory responses that precede β-amyloid-induced neuronal death
por: Merlo, Sara, et al.
Publicado: (2018) -
The Treatment of Impaired Wound Healing in Diabetes: Looking among Old Drugs
por: Spampinato, Simona Federica, et al.
Publicado: (2020) -
Microglia Contributes to BAF-312 Effects on Blood–Brain Barrier Stability
por: Spampinato, Simona Federica, et al.
Publicado: (2022) -
Microglia and the Blood–Brain Barrier: An External Player in Acute and Chronic Neuroinflammatory Conditions
por: Gullotta, Giorgia Serena, et al.
Publicado: (2023)