Joint pre-processing framework for two-dimensional gel electrophoresis images based on nonlinear filtering, background correction and normalization techniques

BACKGROUND: Two-dimensional gel electrophoresis (2-DGE) is a commonly used tool for proteomic analysis. This gel-based technique separates proteins in a sample according to their isoelectric point and molecular weight. 2-DGE images often present anomalies due to the acquisition process, such as: dif...

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Detalles Bibliográficos
Autores principales: Goez, Manuel Mauricio, Torres-Madronero, Maria C., Rothlisberger, Sarah, Delgado-Trejos, Edilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457503/
https://www.ncbi.nlm.nih.gov/pubmed/32867673
http://dx.doi.org/10.1186/s12859-020-03713-0

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