AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations

BACKGROUND: Venous malformations (VMs), most of which associated with activating mutations in the endothelial cells (ECs) tyrosine kinase receptor TIE2, are characterized by dilated and immature veins with scarce smooth muscle cells (SMCs) coverage. However, the underlying mechanism of interaction b...

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Detalles Bibliográficos
Autores principales: Si, Yameng, Huang, Jiadong, Li, Xiang, Fu, Yu, Xu, Rongyao, Du, Yifei, Cheng, Jie, Jiang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457504/
https://www.ncbi.nlm.nih.gov/pubmed/32867785
http://dx.doi.org/10.1186/s12964-020-00606-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457504/
https://www.ncbi.nlm.nih.gov/pubmed/32867785
http://dx.doi.org/10.1186/s12964-020-00606-w

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