Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis

BACKGROUND: Leishmaniasis is a neglected disease caused by Leishmania spp. One of its characteristics is an imbalance of host immune responses to foster parasite survival. In this setting, mesenchymal stromal cells (MSCs) may be a viable therapeutic alternative, given their well-established immunomo...

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Detalles Bibliográficos
Autores principales: Ramos, Tadeu Diniz, Silva, Johnatas Dutra, da Fonseca-Martins, Alessandra Marcia, da Silveira Pratti, Juliana Elena, Firmino-Cruz, Luan, Maciel-Oliveira, Diogo, Dos-Santos, Julio Souza, Tenorio, João Ivo Nunes, de Araujo, Almair Ferreira, Freire-de-Lima, Célio Geraldo, Diaz, Bruno Lourenço, Cruz, Fernanda Ferreira, Rocco, Patricia Rieken Macedo, de Matos Guedes, Herbert Leonel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457509/
https://www.ncbi.nlm.nih.gov/pubmed/32867857
http://dx.doi.org/10.1186/s13287-020-01889-z

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