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Secondary donor-derived humanized CD19-modified CAR-T cells induce remission in relapsed/refractory mixed phenotype acute leukemia after allogeneic hematopoietic stem cell transplantation: a case report

BACKGROUND: Mixed phenotype acute leukemia (MPAL) is a rare leukemia and is regarded as a high-risk entity with a poor prognosis. Induction therapy of an acute lymphoblastic leukemia type or hybrid regimen and hematopoietic stem cell transplantation has been recommended for MPAL. However, the optima...

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Detalles Bibliográficos
Autores principales:	Li, Meng-Yun, Lin, Zhi-Hong, Hu, Ming-Ming, Kang, Li-Qing, Wu, Xiao-xia, Chen, Qi-wei, Kong, Xin, Zhang, Jian, Qiu, Hui-Ying, Wu, De-Pei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457525/ https://www.ncbi.nlm.nih.gov/pubmed/32874588 http://dx.doi.org/10.1186/s40364-020-00216-1

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