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Predicting the most deleterious missense nsSNPs of the protein isoforms of the human HLA-G gene and in silico evaluation of their structural and functional consequences

BACKGROUND: The Human Leukocyte Antigen G (HLA-G) protein is an immune tolerogenic molecule with 7 isoforms. The change of expression level and some polymorphisms of the HLA-G gene are involved in various pathologies. Therefore, this study aimed to predict the most deleterious missense non-synonymou...

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Detalles Bibliográficos
Autores principales:	Emadi, Elaheh, Akhoundi, Fatemeh, Kalantar, Seyed Mehdi, Emadi-Baygi, Modjtaba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457528/ https://www.ncbi.nlm.nih.gov/pubmed/32867672 http://dx.doi.org/10.1186/s12863-020-00890-y

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