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Influence of the amino-terminal sequence on the structure and function of HIV integrase

BACKGROUND: Antiretroviral therapy (ART) can mitigate the morbidity and mortality caused by the human immunodeficiency virus (HIV). Successful development of ART can be accelerated by accurate structural and biochemical data on targets and their responses to inhibitors. One important ART target, HIV...

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Detalles Bibliográficos
Autores principales: Eilers, Grant, Gupta, Kushol, Allen, Audrey, Zhou, Jeffrey, Hwang, Young, Cory, Michael B., Bushman, Frederic D., Van Duyne, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457537/
https://www.ncbi.nlm.nih.gov/pubmed/32867805
http://dx.doi.org/10.1186/s12977-020-00537-x