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Influence of the amino-terminal sequence on the structure and function of HIV integrase
BACKGROUND: Antiretroviral therapy (ART) can mitigate the morbidity and mortality caused by the human immunodeficiency virus (HIV). Successful development of ART can be accelerated by accurate structural and biochemical data on targets and their responses to inhibitors. One important ART target, HIV...
Autores principales: | Eilers, Grant, Gupta, Kushol, Allen, Audrey, Zhou, Jeffrey, Hwang, Young, Cory, Michael B., Bushman, Frederic D., Van Duyne, Gregory |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457537/ https://www.ncbi.nlm.nih.gov/pubmed/32867805 http://dx.doi.org/10.1186/s12977-020-00537-x |
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