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Structure of SARS-CoV-2 ORF8, a rapidly evolving coronavirus protein implicated in immune evasion

The molecular basis for the severity and rapid spread of the COVID-19 disease caused by SARS-CoV-2 is largely unknown. ORF8 is a rapidly evolving accessory protein that has been proposed to interfere with immune responses. The crystal structure of SARS-CoV-2 ORF8 was determined at 2.04 Å resolution...

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Detalles Bibliográficos
Autores principales: Flower, Thomas G., Buffalo, Cosmo Z., Hooy, Richard M., Allaire, Marc, Ren, Xuefeng, Hurley, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457612/
https://www.ncbi.nlm.nih.gov/pubmed/32869027
http://dx.doi.org/10.1101/2020.08.27.270637

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