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Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer

OBJECTIVE: To explore whether protective ileostomy is beneficial in preventing anastomotic leakage after anterior resection of rectal cancer. METHODS: A total of 347 patients underwent anterior resection of rectal cancer in our hospital. Ninety-five patients were treated with protective ileostomy (t...

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Autores principales: Niu, Lei, Wang, Jin, Zhang, Peng, Zhao, Xiaomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457655/
https://www.ncbi.nlm.nih.gov/pubmed/32862745
http://dx.doi.org/10.1177/0300060520946520
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author Niu, Lei
Wang, Jin
Zhang, Peng
Zhao, Xiaomu
author_facet Niu, Lei
Wang, Jin
Zhang, Peng
Zhao, Xiaomu
author_sort Niu, Lei
collection PubMed
description OBJECTIVE: To explore whether protective ileostomy is beneficial in preventing anastomotic leakage after anterior resection of rectal cancer. METHODS: A total of 347 patients underwent anterior resection of rectal cancer in our hospital. Ninety-five patients were treated with protective ileostomy (treatment group), and 252 patients were not (control group). The incidences of anastomotic leakage and permanent stoma were compared between the two groups. RESULTS: The overall incidences of anastomotic leakage were 6.32% (6/95) and 8.73% (22/252) in the treatment group and control group, respectively. In the cohort of patients who underwent neoadjuvant radiotherapy, the incidence of anastomotic leakage was 5.88% (2/34) and 12.0% (3/25) in the treatment group and control group, respectively. Logistic regression showed that the incidence of anastomotic leakage was not statistically significant. However, diabetes and the anastomotic height significantly affected the occurrence of anastomotic leakage. The permanent stoma rate was 6.42% (6/95) and 5.95% (15/252) in the treatment group and control group, respectively. CONCLUSION: Protective ileostomy did not show a significant advantage in reducing the incidence of postoperative anastomotic leakage in patients with rectal cancer, and it may lead to a permanent stoma.
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spelling pubmed-74576552020-09-11 Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer Niu, Lei Wang, Jin Zhang, Peng Zhao, Xiaomu J Int Med Res Retrospective Clinical Research Report OBJECTIVE: To explore whether protective ileostomy is beneficial in preventing anastomotic leakage after anterior resection of rectal cancer. METHODS: A total of 347 patients underwent anterior resection of rectal cancer in our hospital. Ninety-five patients were treated with protective ileostomy (treatment group), and 252 patients were not (control group). The incidences of anastomotic leakage and permanent stoma were compared between the two groups. RESULTS: The overall incidences of anastomotic leakage were 6.32% (6/95) and 8.73% (22/252) in the treatment group and control group, respectively. In the cohort of patients who underwent neoadjuvant radiotherapy, the incidence of anastomotic leakage was 5.88% (2/34) and 12.0% (3/25) in the treatment group and control group, respectively. Logistic regression showed that the incidence of anastomotic leakage was not statistically significant. However, diabetes and the anastomotic height significantly affected the occurrence of anastomotic leakage. The permanent stoma rate was 6.42% (6/95) and 5.95% (15/252) in the treatment group and control group, respectively. CONCLUSION: Protective ileostomy did not show a significant advantage in reducing the incidence of postoperative anastomotic leakage in patients with rectal cancer, and it may lead to a permanent stoma. SAGE Publications 2020-08-29 /pmc/articles/PMC7457655/ /pubmed/32862745 http://dx.doi.org/10.1177/0300060520946520 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Retrospective Clinical Research Report
Niu, Lei
Wang, Jin
Zhang, Peng
Zhao, Xiaomu
Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer
title Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer
title_full Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer
title_fullStr Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer
title_full_unstemmed Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer
title_short Protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer
title_sort protective ileostomy does not prevent anastomotic leakage after anterior resection of rectal cancer
topic Retrospective Clinical Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457655/
https://www.ncbi.nlm.nih.gov/pubmed/32862745
http://dx.doi.org/10.1177/0300060520946520
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