Cargando…

Fatostatin in Combination with Tamoxifen Induces Synergistic Inhibition in ER-Positive Breast Cancer

BACKGROUND: Tamoxifen is the cornerstone of adjuvant therapy for hormone receptor-positive breast cancer. Despite its efficacy, limited drug sensitivity and endocrine resistance remain the important clinical challenges. The main objective of this study was to investigate fatostatin, which was found...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Ying, Zhang, Ning, Zhang, Hanwen, Wang, Lijuan, Duan, Yi, Wang, Xiaolong, Chen, Tong, Liang, Yiran, Li, Yaming, Song, Xiaojin, Li, Chen, Han, Dianwen, Chen, Bing, Zhao, Wenjing, Yang, Qifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457819/ https://www.ncbi.nlm.nih.gov/pubmed/32921987 http://dx.doi.org/10.2147/DDDT.S253876

Ejemplares similares

Fatostatin in Combination with Tamoxifen Induces Synergistic Inhibition in ER-Positive Breast Cancer [Corrigendum]
Publicado: (2022)

circRNA-SFMBT2 orchestrates ERα activation to drive tamoxifen resistance in breast cancer cells
por: Li, Zheng, et al.
Publicado: (2023)

The E3 Ligase TRIM4 Facilitates SET Ubiquitin‐Mediated Degradation to Enhance ER‐α Action in Breast Cancer
por: Han, Dianwen, et al.
Publicado: (2022)

CircEIF3H-IGF2BP2-HuR scaffold complex promotes TNBC progression via stabilizing HSPD1/RBM8A/G3BP1 mRNA
por: Song, Xiaojin, et al.
Publicado: (2022)

Huaier Suppresses Breast Cancer Progression via linc00339/miR-4656/CSNK2B Signaling Pathway
por: Wang, Wei, et al.
Publicado: (2019)

LINC01977 Promotes Breast Cancer Progression and Chemoresistance to Doxorubicin by Targeting miR-212-3p/GOLM1 Axis
por: Li, Zheng, et al.
Publicado: (2021)

LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis
por: Liang, Yiran, et al.
Publicado: (2020)

Retraction Note to: LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis
por: Liang, Yiran, et al.
Publicado: (2022)

A novel long non-coding RNA-PRLB acts as a tumor promoter through regulating miR-4766-5p/SIRT1 axis in breast cancer
por: Liang, Yiran, et al.
Publicado: (2018)

Targeting the circBMPR2/miR-553/USP4 Axis as a Potent Therapeutic Approach for Breast Cancer
por: Liang, Yiran, et al.
Publicado: (2019)

circHMCU Promotes Proliferation and Metastasis of Breast Cancer by Sponging the let-7 Family
por: Song, Xiaojin, et al.
Publicado: (2020)

circHMCU Promotes Proliferationand Metastasis of Breast Cancerby Sponging the let-7 Family
por: Song, Xiaojin, et al.
Publicado: (2021)

Huaier extract synergizes with tamoxifen to induce autophagy and apoptosis in ER-positive breast cancer cells
por: Qi, Wenwen, et al.
Publicado: (2016)

DGUOK-AS1 acts as a tumorpromoter through regulatingmiR-204-5p/IL-11 axis in breast cancer
por: Liang, Yiran, et al.
Publicado: (2021)

Identification and Validation of a Five-Gene Signature Associated With Overall Survival in Breast Cancer Patients
por: Wang, Xiaolong, et al.
Publicado: (2021)

Fatostatin ameliorates inflammation without affecting cell viability
por: Ma, Shuhe, et al.
Publicado: (2022)

Circ-TRIO promotes TNBC progression by regulating the miR-432-5p/CCDC58 axis
por: Wang, Zekun, et al.
Publicado: (2022)

Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma
por: Cai, Jiayang, et al.
Publicado: (2023)

Impact of histotypes on preferential organ‐specific metastasis in triple‐negative breast cancer
por: Li, Yaming, et al.
Publicado: (2019)

Evaluation of efficacy of chemotherapy for mucinous carcinoma: a surveillance, epidemiology, and end results cohort study
por: Zhang, Hanwen, et al.
Publicado: (2020)

Exosomal miR-500a-5p derived from cancer-associated fibroblasts promotes breast cancer cell proliferation and metastasis through targeting USP28
por: Chen, Bing, et al.
Publicado: (2021)

Fatostatin induces pro- and anti-apoptotic lipid accumulation in breast cancer
por: Brovkovych, Viktor, et al.
Publicado: (2018)

Long non-coding RNA MIDEAS-AS1 inhibits growth and metastasis of triple-negative breast cancer via transcriptionally activating NCALD
por: Luo, Dan, et al.
Publicado: (2023)

MiR-770 suppresses the chemo-resistance and metastasis of triple negative breast cancer via direct targeting of STMN1
por: Li, Yaming, et al.
Publicado: (2018)

CircRNA-CREIT inhibits stress granule assembly and overcomes doxorubicin resistance in TNBC by destabilizing PKR
por: Wang, Xiaolong, et al.
Publicado: (2022)

Stratification of Tamoxifen Synergistic Combinations for the Treatment of ER+ Breast Cancer
por: Zboril, Emily K., et al.
Publicado: (2023)

HSPB1 facilitates chemoresistance through inhibiting ferroptotic cancer cell death and regulating NF-κB signaling pathway in breast cancer
por: Liang, Yiran, et al.
Publicado: (2023)

Cancer-associated fibroblasts facilitate breast cancer progression through exosomal circTBPL1-mediated intercellular communication
por: Ye, Fangzhou, et al.
Publicado: (2023)

Huaier extract suppresses breast cancer via regulating tumor-associated macrophages
por: Li, Yaming, et al.
Publicado: (2016)

Histologic heterogeneity predicts patient prognosis of HER2‐positive metastatic breast cancer: A retrospective study based on SEER database
por: Wang, Yajie, et al.
Publicado: (2023)

Hypoxia‐Induced FUS–circTBC1D14 Stress Granules Promote Autophagy in TNBC
por: Liu, Ying, et al.
Publicado: (2023)

Hedgehog pathway is involved in nitidine chloride induced inhibition of epithelial-mesenchymal transition and cancer stem cells-like properties in breast cancer cells
por: Sun, Mingjuan, et al.
Publicado: (2016)

Fatostatin reverses progesterone resistance by inhibiting the SREBP1-NF-κB pathway in endometrial carcinoma
por: Ma, Xiaohong, et al.
Publicado: (2021)

Dose invasive apocrine adenocarcinoma has worse prognosis than invasive ductal carcinoma of breast: evidence from SEER database
por: Zhang, Ning, et al.
Publicado: (2017)

Dynamic surveillance of tamoxifen‐resistance in ER‐positive breast cancer by CAIX‐targeted ultrasound imaging
por: Li, Ying, et al.
Publicado: (2020)

Association of Preoperative Serum Levels of CEA and CA15-3 with Molecular Subtypes of Breast Cancer
por: Zhao, Wenjing, et al.
Publicado: (2021)

Tamoxifen Action in ER-Negative Breast Cancer
por: Manna, Subrata, et al.
Publicado: (2016)

The ERα-miR-575-p27 feedback loop regulates tamoxifen sensitivity in ER-positive Breast Cancer
por: Liu, Shu-Shu, et al.
Publicado: (2020)

LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer
por: Xue, Xingyang, et al.
Publicado: (2015)

miR-221/222 sponge abrogates tamoxifen resistance in ER-positive breast cancer cells through restoring the expression of ERα
por: Ouyang, Yan Xiu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1dsa5qa6nkgngf5paaecen0q7e