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Infection Risk of Lumbar Epidural Injection in the Operating Theatre Prior to Lumbar Fusion Surgery
PURPOSE: To determine the association between preoperative lumbar epidural injections (LEIs) in the operating theater (OR) and the occurrence of surgical site infection (SSI) after posterior lumbar instrumented fusion surgery. METHODS: This study was performed from January 2015 to September 2019. We...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457848/ https://www.ncbi.nlm.nih.gov/pubmed/32922068 http://dx.doi.org/10.2147/JPR.S261922 |
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author | Li, Peng Hou, Xiuwei Gao, Lifeng Zheng, Xiaochen |
author_facet | Li, Peng Hou, Xiuwei Gao, Lifeng Zheng, Xiaochen |
author_sort | Li, Peng |
collection | PubMed |
description | PURPOSE: To determine the association between preoperative lumbar epidural injections (LEIs) in the operating theater (OR) and the occurrence of surgical site infection (SSI) after posterior lumbar instrumented fusion surgery. METHODS: This study was performed from January 2015 to September 2019. We enrolled 2312 patients who underwent lumbar surgery without LEIs (control group) and 469 patients who underwent lumbar surgery after LEIs in the OR. We further separated the patients by the time interval between the LEIs and surgery: 1) for the 0–1 M group, lumbar surgery was performed within 1 month after the LEIs, and 2) for the >1 M group, it was performed more than 1 month after the LEIs. RESULTS: The postoperative infection rate in the 0–1 M group was considerably higher than that in the control group (p = 0.0101). We further subdivided the 0–1 M and >1 M groups into four subgroups: a) the 0–1 MNS group included patients in the 0–1 M group who did not receive steroids; b) the 0–1 MS group who received steroids; c) the >1 MNS group included patients in the >1 M group who did not receive steroids; d) the >1 MS group who received steroids. The postoperative infection rate in the 0–1 MS subgroup was considerably higher than that in the control group (p = 0.0018). However, the infection rate was lower in the >1 MS subgroup (p = 0.1650). There were no statistically significant differences in the postoperative infection rate between the control group and the two non-steroid groups (0–1 MNS group, p = 0.4961; 1 MNS group, p = 0.7381). CONCLUSION: The administration of LEIs without steroids in the OR before lumbar instrumented fusion does not significantly increase patients’ risk of postoperative infection. We recommend avoiding steroid injections administered within 1 month before lumbar instrumented fusion. |
format | Online Article Text |
id | pubmed-7457848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-74578482020-09-11 Infection Risk of Lumbar Epidural Injection in the Operating Theatre Prior to Lumbar Fusion Surgery Li, Peng Hou, Xiuwei Gao, Lifeng Zheng, Xiaochen J Pain Res Original Research PURPOSE: To determine the association between preoperative lumbar epidural injections (LEIs) in the operating theater (OR) and the occurrence of surgical site infection (SSI) after posterior lumbar instrumented fusion surgery. METHODS: This study was performed from January 2015 to September 2019. We enrolled 2312 patients who underwent lumbar surgery without LEIs (control group) and 469 patients who underwent lumbar surgery after LEIs in the OR. We further separated the patients by the time interval between the LEIs and surgery: 1) for the 0–1 M group, lumbar surgery was performed within 1 month after the LEIs, and 2) for the >1 M group, it was performed more than 1 month after the LEIs. RESULTS: The postoperative infection rate in the 0–1 M group was considerably higher than that in the control group (p = 0.0101). We further subdivided the 0–1 M and >1 M groups into four subgroups: a) the 0–1 MNS group included patients in the 0–1 M group who did not receive steroids; b) the 0–1 MS group who received steroids; c) the >1 MNS group included patients in the >1 M group who did not receive steroids; d) the >1 MS group who received steroids. The postoperative infection rate in the 0–1 MS subgroup was considerably higher than that in the control group (p = 0.0018). However, the infection rate was lower in the >1 MS subgroup (p = 0.1650). There were no statistically significant differences in the postoperative infection rate between the control group and the two non-steroid groups (0–1 MNS group, p = 0.4961; 1 MNS group, p = 0.7381). CONCLUSION: The administration of LEIs without steroids in the OR before lumbar instrumented fusion does not significantly increase patients’ risk of postoperative infection. We recommend avoiding steroid injections administered within 1 month before lumbar instrumented fusion. Dove 2020-08-26 /pmc/articles/PMC7457848/ /pubmed/32922068 http://dx.doi.org/10.2147/JPR.S261922 Text en © 2020 Li et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Li, Peng Hou, Xiuwei Gao, Lifeng Zheng, Xiaochen Infection Risk of Lumbar Epidural Injection in the Operating Theatre Prior to Lumbar Fusion Surgery |
title | Infection Risk of Lumbar Epidural Injection in the Operating Theatre Prior to Lumbar Fusion Surgery |
title_full | Infection Risk of Lumbar Epidural Injection in the Operating Theatre Prior to Lumbar Fusion Surgery |
title_fullStr | Infection Risk of Lumbar Epidural Injection in the Operating Theatre Prior to Lumbar Fusion Surgery |
title_full_unstemmed | Infection Risk of Lumbar Epidural Injection in the Operating Theatre Prior to Lumbar Fusion Surgery |
title_short | Infection Risk of Lumbar Epidural Injection in the Operating Theatre Prior to Lumbar Fusion Surgery |
title_sort | infection risk of lumbar epidural injection in the operating theatre prior to lumbar fusion surgery |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457848/ https://www.ncbi.nlm.nih.gov/pubmed/32922068 http://dx.doi.org/10.2147/JPR.S261922 |
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