Cargando…

Using bioinformatics and metabolomics to identify altered granulosa cells in patients with diminished ovarian reserve

BACKGROUND: During fertility treatment, diminished ovarian reserve (DOR) is a challenge that can seriously affect a patient’s reproductive potential. However, the pathogenesis of DOR is still unclear and its treatment options are limited. This study aimed to explore DOR’s molecular mechanisms. METHO...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Ruifen, Zhao, Zhongying, Yang, Yongxiu, Liang, Xiaolei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2020
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457930/ https://www.ncbi.nlm.nih.gov/pubmed/32923184 http://dx.doi.org/10.7717/peerj.9812

Ejemplares similares

Apoptosis of mural granulosa cells is increased in women with diminished ovarian reserve
por: Fan, Yuting, et al.
Publicado: (2019)

The effect of growth hormone on the metabolome of follicular fluid in patients with diminished ovarian reserve
por: He, Fan, et al.
Publicado: (2023)

Potential factors result in diminished ovarian reserve: a comprehensive review
por: Zhu, Qinying, et al.
Publicado: (2023)

Expression of long noncoding RNAs in the ovarian granulosa cells of women with diminished ovarian reserve using high-throughput sequencing
por: Dong, Li, et al.
Publicado: (2022)

Altered Expression of GDF9 and BMP15 Genes in Granulosa Cells of Diminished Ovarian Reserve Patients: A Case-Control Study
por: Omrizadeh, Maryam, et al.
Publicado: (2022)

A bioinformatics approach to identifying Wolbachia infections in arthropods
por: Pascar, Jane, et al.
Publicado: (2018)

The Gengnianchun recipe attenuates insulin resistance-induced diminished ovarian reserve through inhibiting the senescence of granulosa cells
por: Gao, Hongna, et al.
Publicado: (2023)

Identifying optimal bioinformatics protocols for aerosol microbial community data
por: Miaow, Katie, et al.
Publicado: (2021)

Bioinformatics profiling identifies seven immune-related risk signatures for hepatocellular carcinoma
por: Xue, Feng, et al.
Publicado: (2020)

Significance of hub genes and immune cell infiltration identified by bioinformatics analysis in pelvic organ prolapse
por: Zhao, Ying, et al.
Publicado: (2020)

Bioinformatics analysis of microarray data to identify the candidate biomarkers of lung adenocarcinoma
por: Guo, Tingting, et al.
Publicado: (2019)

Synthetic Phenolic Antioxidants and Their Metabolites in Follicular Fluid and Association with Diminished Ovarian Reserve: A Case–Control Study
por: Hao, Yongxiu, et al.
Publicado: (2023)

Bioinformatics analysis identified CDC20 as a potential drug target for cholangiocarcinoma
por: Sungwan, Prin, et al.
Publicado: (2021)

Identifying breast cancer subtypes associated modules and biomarkers by integrated bioinformatics analysis
por: Wang, Yanwei, et al.
Publicado: (2021)

Serum metabolome alterations in patients with early nonalcoholic fatty liver disease
por: Wang, Xuemei, et al.
Publicado: (2022)

Metabolome and transcriptome analyses identify the characteristics and expression of related saponins of the three genealogical plants of bead ginseng
por: Ye, Yihan, et al.
Publicado: (2023)

Identifying multiple collagen gene family members as potential gastric cancer biomarkers using integrated bioinformatics analysis
por: Li, Zhaoxing, et al.
Publicado: (2020)

Sigma-1 receptor is involved in diminished ovarian reserve possibly by influencing endoplasmic reticulum stress-mediated granulosa cells apoptosis
por: Jiang, Lile, et al.
Publicado: (2020)

Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases
por: Boomsma, Wouter, et al.
Publicado: (2016)

Identifying hub genes of papillary thyroid carcinoma in the TCGA and GEO database using bioinformatics analysis
por: Wan, Ying, et al.
Publicado: (2020)

Integrative bioinformatics and experimental analysis revealed down-regulated CDC42EP3 as a novel prognostic target for ovarian cancer and its roles in immune infiltration
por: Yan, Yuanliang, et al.
Publicado: (2021)

Venomix: a simple bioinformatic pipeline for identifying and characterizing toxin gene candidates from transcriptomic data
por: Macrander, Jason, et al.
Publicado: (2018)

Bioinformatical analysis identifies PDLIM3 as a potential biomarker associated with immune infiltration in patients with endometriosis
por: Gan, Lei, et al.
Publicado: (2022)

In vitro fertilization outcomes in women with surgery induced diminished ovarian reserve after endometrioma operation: Comparison with diminished ovarian reserve without ovarian surgery
por: Hong, Su Been, et al.
Publicado: (2017)

UHPLC-MS-MS analysis of oxylipins metabolomics components of follicular fluid in infertile individuals with diminished ovarian reserve
por: Liang, Chengcheng, et al.
Publicado: (2021)

Mir-484 contributes to diminished ovarian reserve by regulating granulosa cell function via YAP1-mediated mitochondrial function and apoptosis
por: Li, Huiying, et al.
Publicado: (2022)

High Housing Density-Induced Chronic Stress Diminishes Ovarian Reserve via Granulosa Cell Apoptosis by Angiotensin II Overexpression in Mice
por: Kim, Jihyun, et al.
Publicado: (2022)

Identification of MEG8/miR‐378d/SOBP axis as a novel regulatory network and associated with immune infiltrates in ovarian carcinoma by integrated bioinformatics analysis
por: Lei, Jian, et al.
Publicado: (2021)

Effects of vitamin D supplementation on ovarian reserve markers in infertile women with diminished ovarian reserve
por: Bacanakgil, Besim Haluk, et al.
Publicado: (2022)

Dehydroepiandrosterone (DHEA) supplementation in diminished ovarian reserve (DOR)
por: Gleicher, Norbert, et al.
Publicado: (2011)

In vitro fertilization outcome in women with diminished ovarian reserve
por: Yun, Bo Hyon, et al.
Publicado: (2017)

Pueratin improves diminished ovarian reserve by inhibiting apoptosis
por: Qi, Quan, et al.
Publicado: (2021)

Bioinformatic analysis identifies potentially key differentially expressed genes in oncogenesis and progression of clear cell renal cell carcinoma
por: Zhang, Haiping, et al.
Publicado: (2019)

Integrative analysis of miRNA–mRNA network in idiopathic membranous nephropathy by bioinformatics analysis
por: He, Wenfang, et al.
Publicado: (2021)

Tumor-preventing activity of aspirin in multiple cancers based on bioinformatic analyses
por: Li, Diangeng, et al.
Publicado: (2018)

Bioinformatics and the Metaverse: Are We Ready?
por: Taylor, Stephen, et al.
Publicado: (2022)

miR‐221‐3p regulates apoptosis of ovarian granulosa cells via targeting FOXO1 in older women with diminished ovarian reserve (DOR)
por: Wei, Chaofeng, et al.
Publicado: (2021)

Identified a disintegrin and metalloproteinase with thrombospondin motifs 6 serve as a novel gastric cancer prognostic biomarker by bioinformatics analysis
por: Zhu, Ya-zhen, et al.
Publicado: (2021)

Identifying C1QB, ITGAM, and ITGB2 as potential diagnostic candidate genes for diabetic nephropathy using bioinformatics analysis
por: Hu, Yongzheng, et al.
Publicado: (2023)

The expression of small RNAs in exosomes of follicular fluid altered in human polycystic ovarian syndrome
por: Hu, Junhe, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ljn5keq35uo9ntfuhakfsqhf3e