Cargando…

Racial-Ethnic Inequity in Young Adults With Type 1 Diabetes

CONTEXT: Minority young adults (YA) currently represent the largest growing population with type 1 diabetes (T1D) and experience very poor outcomes. Modifiable drivers of disparities need to be identified, but are not well-studied. OBJECTIVE: To describe racial-ethnic disparities among YA with T1D a...

Descripción completa

Detalles Bibliográficos
Autores principales: Agarwal, Shivani, Kanapka, Lauren G, Raymond, Jennifer K, Walker, Ashby, Gerard-Gonzalez, Andrea, Kruger, Davida, Redondo, Maria J, Rickels, Michael R, Shah, Viral N, Butler, Ashley, Gonzalez, Jeffrey, Verdejo, Alandra S, Gal, Robin L, Willi, Steven, Long, Judith A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457963/
https://www.ncbi.nlm.nih.gov/pubmed/32382736
http://dx.doi.org/10.1210/clinem/dgaa236
_version_ 1783576101046452224
author Agarwal, Shivani
Kanapka, Lauren G
Raymond, Jennifer K
Walker, Ashby
Gerard-Gonzalez, Andrea
Kruger, Davida
Redondo, Maria J
Rickels, Michael R
Shah, Viral N
Butler, Ashley
Gonzalez, Jeffrey
Verdejo, Alandra S
Gal, Robin L
Willi, Steven
Long, Judith A
author_facet Agarwal, Shivani
Kanapka, Lauren G
Raymond, Jennifer K
Walker, Ashby
Gerard-Gonzalez, Andrea
Kruger, Davida
Redondo, Maria J
Rickels, Michael R
Shah, Viral N
Butler, Ashley
Gonzalez, Jeffrey
Verdejo, Alandra S
Gal, Robin L
Willi, Steven
Long, Judith A
author_sort Agarwal, Shivani
collection PubMed
description CONTEXT: Minority young adults (YA) currently represent the largest growing population with type 1 diabetes (T1D) and experience very poor outcomes. Modifiable drivers of disparities need to be identified, but are not well-studied. OBJECTIVE: To describe racial-ethnic disparities among YA with T1D and identify drivers of glycemic disparity other than socioeconomic status (SES). DESIGN: Cross-sectional multicenter collection of patient and chart-reported variables, including SES, social determinants of health, and diabetes-specific factors, with comparison between non-Hispanic White, non-Hispanic Black, and Hispanic YA and multilevel modeling to identify variables that account for glycemic disparity apart from SES. SETTING: Six diabetes centers across the United States. PARTICIPANTS: A total of 300 YA with T1D (18-28 years: 33% non-Hispanic White, 32% non-Hispanic Black, and 34% Hispanic). MAIN OUTCOME: Racial-ethnic disparity in HbA1c levels. RESULTS: Non-Hispanic Black and Hispanic YA had lower SES, higher HbA1c levels, and much lower diabetes technology use than non-Hispanic White YA (P < 0.001). Non-Hispanic Black YA differed from Hispanic, reporting higher diabetes distress and lower self-management (P < 0.001). After accounting for SES, differences in HbA1c levels disappeared between non-Hispanic White and Hispanic YA, whereas they remained for non-Hispanic Black YA (+ 2.26% [24 mmol/mol], P < 0.001). Diabetes technology use, diabetes distress, and disease self-management accounted for a significant portion of the remaining non-Hispanic Black–White glycemic disparity. CONCLUSION: This study demonstrated large racial-ethnic inequity in YA with T1D, especially among non-Hispanic Black participants. Our findings reveal key opportunities for clinicians to potentially mitigate glycemic disparity in minority YA by promoting diabetes technology use, connecting with social programs, and tailoring support for disease self-management and diabetes distress to account for social contextual factors.
format Online
Article
Text
id pubmed-7457963
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-74579632020-09-04 Racial-Ethnic Inequity in Young Adults With Type 1 Diabetes Agarwal, Shivani Kanapka, Lauren G Raymond, Jennifer K Walker, Ashby Gerard-Gonzalez, Andrea Kruger, Davida Redondo, Maria J Rickels, Michael R Shah, Viral N Butler, Ashley Gonzalez, Jeffrey Verdejo, Alandra S Gal, Robin L Willi, Steven Long, Judith A J Clin Endocrinol Metab Online Only Articles CONTEXT: Minority young adults (YA) currently represent the largest growing population with type 1 diabetes (T1D) and experience very poor outcomes. Modifiable drivers of disparities need to be identified, but are not well-studied. OBJECTIVE: To describe racial-ethnic disparities among YA with T1D and identify drivers of glycemic disparity other than socioeconomic status (SES). DESIGN: Cross-sectional multicenter collection of patient and chart-reported variables, including SES, social determinants of health, and diabetes-specific factors, with comparison between non-Hispanic White, non-Hispanic Black, and Hispanic YA and multilevel modeling to identify variables that account for glycemic disparity apart from SES. SETTING: Six diabetes centers across the United States. PARTICIPANTS: A total of 300 YA with T1D (18-28 years: 33% non-Hispanic White, 32% non-Hispanic Black, and 34% Hispanic). MAIN OUTCOME: Racial-ethnic disparity in HbA1c levels. RESULTS: Non-Hispanic Black and Hispanic YA had lower SES, higher HbA1c levels, and much lower diabetes technology use than non-Hispanic White YA (P < 0.001). Non-Hispanic Black YA differed from Hispanic, reporting higher diabetes distress and lower self-management (P < 0.001). After accounting for SES, differences in HbA1c levels disappeared between non-Hispanic White and Hispanic YA, whereas they remained for non-Hispanic Black YA (+ 2.26% [24 mmol/mol], P < 0.001). Diabetes technology use, diabetes distress, and disease self-management accounted for a significant portion of the remaining non-Hispanic Black–White glycemic disparity. CONCLUSION: This study demonstrated large racial-ethnic inequity in YA with T1D, especially among non-Hispanic Black participants. Our findings reveal key opportunities for clinicians to potentially mitigate glycemic disparity in minority YA by promoting diabetes technology use, connecting with social programs, and tailoring support for disease self-management and diabetes distress to account for social contextual factors. Oxford University Press 2020-05-08 /pmc/articles/PMC7457963/ /pubmed/32382736 http://dx.doi.org/10.1210/clinem/dgaa236 Text en © Endocrine Society 2020. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Online Only Articles
Agarwal, Shivani
Kanapka, Lauren G
Raymond, Jennifer K
Walker, Ashby
Gerard-Gonzalez, Andrea
Kruger, Davida
Redondo, Maria J
Rickels, Michael R
Shah, Viral N
Butler, Ashley
Gonzalez, Jeffrey
Verdejo, Alandra S
Gal, Robin L
Willi, Steven
Long, Judith A
Racial-Ethnic Inequity in Young Adults With Type 1 Diabetes
title Racial-Ethnic Inequity in Young Adults With Type 1 Diabetes
title_full Racial-Ethnic Inequity in Young Adults With Type 1 Diabetes
title_fullStr Racial-Ethnic Inequity in Young Adults With Type 1 Diabetes
title_full_unstemmed Racial-Ethnic Inequity in Young Adults With Type 1 Diabetes
title_short Racial-Ethnic Inequity in Young Adults With Type 1 Diabetes
title_sort racial-ethnic inequity in young adults with type 1 diabetes
topic Online Only Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457963/
https://www.ncbi.nlm.nih.gov/pubmed/32382736
http://dx.doi.org/10.1210/clinem/dgaa236
work_keys_str_mv AT agarwalshivani racialethnicinequityinyoungadultswithtype1diabetes
AT kanapkalaureng racialethnicinequityinyoungadultswithtype1diabetes
AT raymondjenniferk racialethnicinequityinyoungadultswithtype1diabetes
AT walkerashby racialethnicinequityinyoungadultswithtype1diabetes
AT gerardgonzalezandrea racialethnicinequityinyoungadultswithtype1diabetes
AT krugerdavida racialethnicinequityinyoungadultswithtype1diabetes
AT redondomariaj racialethnicinequityinyoungadultswithtype1diabetes
AT rickelsmichaelr racialethnicinequityinyoungadultswithtype1diabetes
AT shahviraln racialethnicinequityinyoungadultswithtype1diabetes
AT butlerashley racialethnicinequityinyoungadultswithtype1diabetes
AT gonzalezjeffrey racialethnicinequityinyoungadultswithtype1diabetes
AT verdejoalandras racialethnicinequityinyoungadultswithtype1diabetes
AT galrobinl racialethnicinequityinyoungadultswithtype1diabetes
AT willisteven racialethnicinequityinyoungadultswithtype1diabetes
AT longjuditha racialethnicinequityinyoungadultswithtype1diabetes