Anticoagulation in COVID-19: A Systematic Review, Meta-analysis, and Rapid Guidance From Mayo Clinic

A higher risk of thrombosis has been described as a prominent feature of coronavirus disease 2019 (COVID-19). This systematic review synthesizes current data on thrombosis risk, prognostic implications, and anticoagulation effects in COVID-19. We included 37 studies from 4070 unique citations. Meta-...

Descripción completa

Detalles Bibliográficos
Autores principales: McBane, Robert D., Torres Roldan, Victor D., Niven, Alexander S., Pruthi, Rajiv K., Franco, Pablo Moreno, Linderbaum, Jane A., Casanegra, Ana I., Oyen, Lance J., Houghton, Damon E., Marshall, Ariela L., Ou, Narith N., Siegel, Jason L., Wysokinski, Waldemar E., Padrnos, Leslie J., Rivera, Candido E., Flo, Gayle L., Shamoun, Fadi E., Silvers, Scott M., Nayfeh, Tarek, Urtecho, Meritxell, Shah, Sahrish, Benkhadra, Raed, Saadi, Samer Mohir, Firwana, Mohammed, Jawaid, Tabinda, Amin, Mustapha, Prokop, Larry J., Murad, M. Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mayo Foundation for Medical Education and Research 2020
Materias:
Consensus Recommendation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458092/
https://www.ncbi.nlm.nih.gov/pubmed/33153635
http://dx.doi.org/10.1016/j.mayocp.2020.08.030
Descripción
Sumario:A higher risk of thrombosis has been described as a prominent feature of coronavirus disease 2019 (COVID-19). This systematic review synthesizes current data on thrombosis risk, prognostic implications, and anticoagulation effects in COVID-19. We included 37 studies from 4070 unique citations. Meta-analysis was performed when feasible. Coagulopathy and thrombotic events were frequent among patients with COVID-19 and further increased in those with more severe forms of the disease. We also present guidance on the prevention and management of thrombosis from a multidisciplinary panel of specialists from Mayo Clinic. The current certainty of evidence is generally very low and continues to evolve.

Ejemplares similares