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Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread
Metastatic breast carcinoma is a relatively common clinical entity. However, the prognosis of oligometastatic and polygometastatic disease differs considerably pertaining to five-year survival. Metastatic breast carcinoma to the sternum has been described as early as 1988. We describe two cases in o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458144/ https://www.ncbi.nlm.nih.gov/pubmed/32904681 http://dx.doi.org/10.1093/jscr/rjaa272 |
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author | Mohamed, Saifullah Mazhar, Khurum Osman, Ahmed Patel, Akshay Srinivasan, Lakshmi Ghosh, Shilajit |
author_facet | Mohamed, Saifullah Mazhar, Khurum Osman, Ahmed Patel, Akshay Srinivasan, Lakshmi Ghosh, Shilajit |
author_sort | Mohamed, Saifullah |
collection | PubMed |
description | Metastatic breast carcinoma is a relatively common clinical entity. However, the prognosis of oligometastatic and polygometastatic disease differs considerably pertaining to five-year survival. Metastatic breast carcinoma to the sternum has been described as early as 1988. We describe two cases in our institution who presented with solitary sternal metastases with a previous history of treated breast cancer. In both cases, there had been a history of previous left breast cancer treated aggressively with surgical resection and adjuvant oncological therapy and maintenance hormonal therapy. Partial sternectomy or total sternectomy for solitary metastatic sternal deposits is well established with relatively low morbidity and mortality and improvement in quality of life and possible improvement in long-term survival. Furthermore, reconstructive options are inherently dependent on extent of resection performed. These techniques can incorporate the use of sternal plates in order to approximate defects and reinforce the sternum in the setting of partial sternectomy. |
format | Online Article Text |
id | pubmed-7458144 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-74581442020-09-03 Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread Mohamed, Saifullah Mazhar, Khurum Osman, Ahmed Patel, Akshay Srinivasan, Lakshmi Ghosh, Shilajit J Surg Case Rep Case Report Metastatic breast carcinoma is a relatively common clinical entity. However, the prognosis of oligometastatic and polygometastatic disease differs considerably pertaining to five-year survival. Metastatic breast carcinoma to the sternum has been described as early as 1988. We describe two cases in our institution who presented with solitary sternal metastases with a previous history of treated breast cancer. In both cases, there had been a history of previous left breast cancer treated aggressively with surgical resection and adjuvant oncological therapy and maintenance hormonal therapy. Partial sternectomy or total sternectomy for solitary metastatic sternal deposits is well established with relatively low morbidity and mortality and improvement in quality of life and possible improvement in long-term survival. Furthermore, reconstructive options are inherently dependent on extent of resection performed. These techniques can incorporate the use of sternal plates in order to approximate defects and reinforce the sternum in the setting of partial sternectomy. Oxford University Press 2020-08-31 /pmc/articles/PMC7458144/ /pubmed/32904681 http://dx.doi.org/10.1093/jscr/rjaa272 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Mohamed, Saifullah Mazhar, Khurum Osman, Ahmed Patel, Akshay Srinivasan, Lakshmi Ghosh, Shilajit Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread |
title | Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread |
title_full | Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread |
title_fullStr | Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread |
title_full_unstemmed | Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread |
title_short | Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread |
title_sort | excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458144/ https://www.ncbi.nlm.nih.gov/pubmed/32904681 http://dx.doi.org/10.1093/jscr/rjaa272 |
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