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Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread

Metastatic breast carcinoma is a relatively common clinical entity. However, the prognosis of oligometastatic and polygometastatic disease differs considerably pertaining to five-year survival. Metastatic breast carcinoma to the sternum has been described as early as 1988. We describe two cases in o...

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Autores principales: Mohamed, Saifullah, Mazhar, Khurum, Osman, Ahmed, Patel, Akshay, Srinivasan, Lakshmi, Ghosh, Shilajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458144/
https://www.ncbi.nlm.nih.gov/pubmed/32904681
http://dx.doi.org/10.1093/jscr/rjaa272
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author Mohamed, Saifullah
Mazhar, Khurum
Osman, Ahmed
Patel, Akshay
Srinivasan, Lakshmi
Ghosh, Shilajit
author_facet Mohamed, Saifullah
Mazhar, Khurum
Osman, Ahmed
Patel, Akshay
Srinivasan, Lakshmi
Ghosh, Shilajit
author_sort Mohamed, Saifullah
collection PubMed
description Metastatic breast carcinoma is a relatively common clinical entity. However, the prognosis of oligometastatic and polygometastatic disease differs considerably pertaining to five-year survival. Metastatic breast carcinoma to the sternum has been described as early as 1988. We describe two cases in our institution who presented with solitary sternal metastases with a previous history of treated breast cancer. In both cases, there had been a history of previous left breast cancer treated aggressively with surgical resection and adjuvant oncological therapy and maintenance hormonal therapy. Partial sternectomy or total sternectomy for solitary metastatic sternal deposits is well established with relatively low morbidity and mortality and improvement in quality of life and possible improvement in long-term survival. Furthermore, reconstructive options are inherently dependent on extent of resection performed. These techniques can incorporate the use of sternal plates in order to approximate defects and reinforce the sternum in the setting of partial sternectomy.
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spelling pubmed-74581442020-09-03 Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread Mohamed, Saifullah Mazhar, Khurum Osman, Ahmed Patel, Akshay Srinivasan, Lakshmi Ghosh, Shilajit J Surg Case Rep Case Report Metastatic breast carcinoma is a relatively common clinical entity. However, the prognosis of oligometastatic and polygometastatic disease differs considerably pertaining to five-year survival. Metastatic breast carcinoma to the sternum has been described as early as 1988. We describe two cases in our institution who presented with solitary sternal metastases with a previous history of treated breast cancer. In both cases, there had been a history of previous left breast cancer treated aggressively with surgical resection and adjuvant oncological therapy and maintenance hormonal therapy. Partial sternectomy or total sternectomy for solitary metastatic sternal deposits is well established with relatively low morbidity and mortality and improvement in quality of life and possible improvement in long-term survival. Furthermore, reconstructive options are inherently dependent on extent of resection performed. These techniques can incorporate the use of sternal plates in order to approximate defects and reinforce the sternum in the setting of partial sternectomy. Oxford University Press 2020-08-31 /pmc/articles/PMC7458144/ /pubmed/32904681 http://dx.doi.org/10.1093/jscr/rjaa272 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Mohamed, Saifullah
Mazhar, Khurum
Osman, Ahmed
Patel, Akshay
Srinivasan, Lakshmi
Ghosh, Shilajit
Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread
title Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread
title_full Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread
title_fullStr Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread
title_full_unstemmed Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread
title_short Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread
title_sort excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458144/
https://www.ncbi.nlm.nih.gov/pubmed/32904681
http://dx.doi.org/10.1093/jscr/rjaa272
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