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Collagenous colitis in a child induced by chronic respiratory allergy: A case report

INTRODUCTION: Collagen colitis (CC) is a microscopic colitis diagnosed by mucosal biopsy and is extremely rare in children. PATIENT CONCERNS: We reported a child with severe persistent diarrhea that could not be relieved with traditional diarrheal treatment. No abnormalities were found after multipl...

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Autores principales: Wan, Xue-Meng, Wang, Zhi-Ling, Wang, Li-Yuan, Cai, Xiao-Tang, Wan, Chao-Min, Xie, Yong-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458195/
https://www.ncbi.nlm.nih.gov/pubmed/32871927
http://dx.doi.org/10.1097/MD.0000000000021920
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author Wan, Xue-Meng
Wang, Zhi-Ling
Wang, Li-Yuan
Cai, Xiao-Tang
Wan, Chao-Min
Xie, Yong-Mei
author_facet Wan, Xue-Meng
Wang, Zhi-Ling
Wang, Li-Yuan
Cai, Xiao-Tang
Wan, Chao-Min
Xie, Yong-Mei
author_sort Wan, Xue-Meng
collection PubMed
description INTRODUCTION: Collagen colitis (CC) is a microscopic colitis diagnosed by mucosal biopsy and is extremely rare in children. PATIENT CONCERNS: We reported a child with severe persistent diarrhea that could not be relieved with traditional diarrheal treatment. No abnormalities were found after multiple colonoscopies. DIAGNOSES: A significant increase in total IgE levels was found in the patient's blood. He had a history of mild chronic allergic rhinitis and slightly intermittent wheezing. However, we found that the child had a hyperallergic reaction to multiple respiratory antigens and had mild pulmonary dysfunction. Finally, colonoscopy with biopsy identified the diagnosis of CC. INTERVENTION: Considering that a respiratory allergic reaction was one of the causes of diarrhea, anti-allergic treatment was given to the child, and his severe diarrhea was soon relieved. Corticosteroid treatment was suggested to the patient, but his parents firmly refused steroid therapy. According to the patient's specific allergic reaction to mites, desensitization treatment was finally chosen for him. OUTCOMES: After 1 year of desensitization for dust mites, the patient's respiratory symptoms improved, total IgE levels decreased, autoantibodies declined, and diarrhea did not reoccur. Colonoscopy with biopsy showed a significant improvement in pathology. CONCLUSION: CC in children is rare, and childhood CC induced by a respiratory allergic reaction has not been previously reported. Therefore, this is a special case of CC in a patient who was cured with anti-allergy treatments and desensitization instead of steroid therapy.
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spelling pubmed-74581952020-09-11 Collagenous colitis in a child induced by chronic respiratory allergy: A case report Wan, Xue-Meng Wang, Zhi-Ling Wang, Li-Yuan Cai, Xiao-Tang Wan, Chao-Min Xie, Yong-Mei Medicine (Baltimore) 6200 INTRODUCTION: Collagen colitis (CC) is a microscopic colitis diagnosed by mucosal biopsy and is extremely rare in children. PATIENT CONCERNS: We reported a child with severe persistent diarrhea that could not be relieved with traditional diarrheal treatment. No abnormalities were found after multiple colonoscopies. DIAGNOSES: A significant increase in total IgE levels was found in the patient's blood. He had a history of mild chronic allergic rhinitis and slightly intermittent wheezing. However, we found that the child had a hyperallergic reaction to multiple respiratory antigens and had mild pulmonary dysfunction. Finally, colonoscopy with biopsy identified the diagnosis of CC. INTERVENTION: Considering that a respiratory allergic reaction was one of the causes of diarrhea, anti-allergic treatment was given to the child, and his severe diarrhea was soon relieved. Corticosteroid treatment was suggested to the patient, but his parents firmly refused steroid therapy. According to the patient's specific allergic reaction to mites, desensitization treatment was finally chosen for him. OUTCOMES: After 1 year of desensitization for dust mites, the patient's respiratory symptoms improved, total IgE levels decreased, autoantibodies declined, and diarrhea did not reoccur. Colonoscopy with biopsy showed a significant improvement in pathology. CONCLUSION: CC in children is rare, and childhood CC induced by a respiratory allergic reaction has not been previously reported. Therefore, this is a special case of CC in a patient who was cured with anti-allergy treatments and desensitization instead of steroid therapy. Lippincott Williams & Wilkins 2020-08-28 /pmc/articles/PMC7458195/ /pubmed/32871927 http://dx.doi.org/10.1097/MD.0000000000021920 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 6200
Wan, Xue-Meng
Wang, Zhi-Ling
Wang, Li-Yuan
Cai, Xiao-Tang
Wan, Chao-Min
Xie, Yong-Mei
Collagenous colitis in a child induced by chronic respiratory allergy: A case report
title Collagenous colitis in a child induced by chronic respiratory allergy: A case report
title_full Collagenous colitis in a child induced by chronic respiratory allergy: A case report
title_fullStr Collagenous colitis in a child induced by chronic respiratory allergy: A case report
title_full_unstemmed Collagenous colitis in a child induced by chronic respiratory allergy: A case report
title_short Collagenous colitis in a child induced by chronic respiratory allergy: A case report
title_sort collagenous colitis in a child induced by chronic respiratory allergy: a case report
topic 6200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458195/
https://www.ncbi.nlm.nih.gov/pubmed/32871927
http://dx.doi.org/10.1097/MD.0000000000021920
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