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Improved Parkinsons disease motor score in a single-arm open-label trial of febuxostat and inosine
BACKGROUND: Cellular energetics play an important role in Parkinsons disease etiology, but no treatments directly address this deficiency. Our past research showed that treatment with febuxostat and inosine increased blood hypoxanthine and ATP in healthy adults, and a preliminary trial in 3 Parkinso...
Autores principales: | Watanabe, Hirohisa, Hattori, Tatsuya, Kume, Akito, Misu, Kenichiro, Ito, Takashi, Koike, Yu, Johnson, Todd A., Kamitsuji, Shigeo, Kamatani, Naoyuki, Sobue, Gen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458241/ https://www.ncbi.nlm.nih.gov/pubmed/32871874 http://dx.doi.org/10.1097/MD.0000000000021576 |
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