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The constitutive activity of the viral-encoded G protein-coupled receptor US28 supports a complex signalling network contributing to cancer development

US28 is a viral G protein-coupled receptor (GPCR) encoded by the human cytomegalovirus (HCMV). This receptor, expressed both during lytic replication and viral latency, is required for latency. US28 is binding to a wide variety of chemokines but also exhibits a particularly high constitutive activit...

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Detalles Bibliográficos
Autores principales:	Daly, Carole A., Smit, Martine J., Plouffe, Bianca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458396/ https://www.ncbi.nlm.nih.gov/pubmed/32779712 http://dx.doi.org/10.1042/BST20190988

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