A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers

Around 40% of humans and Tasmanian devils (Sarcophilus harrisii) develop cancer in their lifetime, compared to less than 10% for most species. In addition, devils are affected by two of the three known transmissible cancers in mammals. Immune checkpoint immunotherapy has transformed human medicine,...

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Detalles Bibliográficos
Autores principales: Flies, Andrew S., Darby, Jocelyn M., Lennard, Patrick R., Murphy, Peter R., Ong, Chrissie E. B., Pinfold, Terry L., De Luca, Alana, Lyons, A. Bruce, Woods, Gregory M., Patchett, Amanda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458443/
https://www.ncbi.nlm.nih.gov/pubmed/32937435
http://dx.doi.org/10.1126/sciadv.aba5031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458443/
https://www.ncbi.nlm.nih.gov/pubmed/32937435
http://dx.doi.org/10.1126/sciadv.aba5031

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