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A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers
Around 40% of humans and Tasmanian devils (Sarcophilus harrisii) develop cancer in their lifetime, compared to less than 10% for most species. In addition, devils are affected by two of the three known transmissible cancers in mammals. Immune checkpoint immunotherapy has transformed human medicine,...
Autores principales: | Flies, Andrew S., Darby, Jocelyn M., Lennard, Patrick R., Murphy, Peter R., Ong, Chrissie E. B., Pinfold, Terry L., De Luca, Alana, Lyons, A. Bruce, Woods, Gregory M., Patchett, Amanda L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458443/ https://www.ncbi.nlm.nih.gov/pubmed/32937435 http://dx.doi.org/10.1126/sciadv.aba5031 |
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