Identification of human CD4(+) T cell populations with distinct antitumor activity

How naturally arising human CD4(+) T helper subsets affect cancer immunotherapy is unclear. We reported that human CD4(+)CD26(high) T cells elicit potent immunity against solid tumors. As CD26(high) T cells are often categorized as T(H)17 cells for their IL-17 production and high CD26 expression, we...

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Detalles Bibliográficos
Autores principales: Nelson, Michelle H., Knochelmann, Hannah M., Bailey, Stefanie R., Huff, Logan W., Bowers, Jacob S., Majchrzak-Kuligowska, Kinga, Wyatt, Megan M., Rubinstein, Mark P., Mehrotra, Shikhar, Nishimura, Michael I., Armeson, Kent E., Giresi, Paul G., Zilliox, Michael J., Broxmeyer, Hal E., Paulos, Chrystal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458458/
https://www.ncbi.nlm.nih.gov/pubmed/32937437
http://dx.doi.org/10.1126/sciadv.aba7443

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