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DeepH&M: Estimating single-CpG hydroxymethylation and methylation levels from enrichment and restriction enzyme sequencing methods

Increased appreciation of 5-hydroxymethylcytosine (5hmC) as a stable epigenetic mark, which defines cell identity and disease progress, has engendered a need for cost-effective, but high-resolution, 5hmC mapping technology. Current enrichment-based technologies provide cheap but low-resolution and r...

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Detalles Bibliográficos
Autores principales: He, Yu, Jang, Hyo Sik, Xing, Xiaoyun, Li, Daofeng, Vasek, Michael J., Dougherty, Joseph D., Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458459/
https://www.ncbi.nlm.nih.gov/pubmed/32937429
http://dx.doi.org/10.1126/sciadv.aba0521

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