COVID-19 and the endothelium

There is growing evidence that COVID-19 not only affects the lungs but beyond that the endothelial system. Recent studies showed that this can lead to microcirculatory impairments and in consequence to functional disorders of all inner organs. The combination of endothelial dysfunction with a genera...

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Detalles Bibliográficos
Autores principales: Jung, F., Krüger-Genge, A., Franke, R.P., Hufert, F., Küpper, J.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Short Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458498/
https://www.ncbi.nlm.nih.gov/pubmed/32568187
http://dx.doi.org/10.3233/CH-209007
Descripción
Sumario:There is growing evidence that COVID-19 not only affects the lungs but beyond that the endothelial system. Recent studies showed that this can lead to microcirculatory impairments and in consequence to functional disorders of all inner organs. The combination of endothelial dysfunction with a generalized inflammatory state and complement elements may together contribute to the overall pro-coagulative state described in COVID-19 patients leading to venular as well as to arteriolar occlusions.

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